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Gross Cystic Fluid Protein 15 (GCDFP-15)

Methodology

IHC

Specimen Requirements

To perform IHC testing, we request formalin-fixed, paraffin-embedded tissue samples. Please ensure that the blocks are clearly labeled with the patient name or identifier, date of birth and type of sample (tumor, normal). Additionally, a copy of the pathology report accompanying the tissue block will be very helpful. If tissue blocks are not available, we will also accept unstained slides (please submit 1-2 slides per antibody to be tested, cuts must be 4 microns thick).

Clinical Significance

This antibody is specific to a 15 kDa monomer protein called Gross Cystic Disease Fluid Protein-15 (GCDFP-15). GCDFP15 is expressed in apocrine epithelia, lacrimal, ceruminous and Moll’s glands as well as in numerous serous cells of the submandibular, tracheal, bronchial, sublingual and minor salivary glands. It can be of use in the identification of breast carcinoma, salivary duct carcinoma and apocrine epithelia.

CPT Code(s)

88342 The listed CPT codes are for reference use only. These codes should not direct billing practices and may not accurately reflect current Clarient billing practices.

Turnaround Time

24 Hours

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