TEST MENU

Actin - Muscle Specific (MSA)

Four muscle actins have been identified; skeletal alpha, cardial alpha, vascular smooth muscle ...

Actin - Smooth Muscle (SMA)

Actin is one of two major cytoskeletal proteins involved in cell motility. Smooth muscle actin ...

Adenovirus

Useful in identification of adenovirus.

Adrenocorticotropin Hormone (ACTH)

Anti-adrenocorticotropic hormone (ACTH) is a useful marker in the classification of pituitary ...

Alpha Fetoprotein (AFP)

Alpha-1-fetoprotein (AFP) is a 64 kD tumor-associated embryonal antigen produced by fetal liver, ...

Alpha-1-Antichymotrypsin (AACT)

This antibody labels the cytoplasm of histiocytes and neoplasms of histiocytic origin, such ...

Alpha-1-Antitrypsin (AAT)

The immunohistochemical staining of Alpha-1-Antitrypsin is considered to be very useful in ...

Amyloid A

This antibody reacts with amyloid deposits in all tissues including kidney and rectum.

Amyloid P

The antibody reacts with amyloid P component in all tissues.

Anaplastic Lymphoma Kinase (ALK1)

ALK is the protein of the anaplastic lymphoma kinase gene. The protein is not normally detectable ...

Androgen Receptor (AR)

Androgen receptor is responsible for the regulation of the growth of the prostate epithelial ...

B72.3

Monoclonal antibodies (B72.3) to tumor-associated glycoprotein recognizes a tumor-associated ...

Bartonella Henselae

Identifies bartonella henselae.

BCA-225

This antibody recognizes a human breast carcinoma associated glycoprotein BCA-225 (220-225kD). ...

BCL1

IGH/CCND1 is a cell cycle regulatory protein identified through the 11;14 translocation of ...

BCL2

Useful in the identification of follicular lymphomas. Overexpression of BCL2 is in higher grade ...

BCL6

BCL6 is a transcriptional regulator gene that codes for a 706-amino-acid nuclear zinc finger ...

BerEP4

The antibody to Ber-EP4 shows a very broad pattern of reactivity with human epithelial tissues ...

Beta Amyloid

Beta amyloid is an extracellular filamentous protein deposit found in Alzheimer's diseased ...

Beta-Catenin

b-Catenin is an important regulator of cell–cell adhesion and embryogenesis and there is evidence ...

BG-8

This antibody is specific for Lewis Y (Type 2 Chain). The Lewis Y has been evaluated as a clinical ...

BOB1

OCT2 is present in all B-cells expressing Ig. The combination of BOB1 and OCT2 stains is helpful ...

BRCA1

BRCA1 gene mutations are responsible for about 40% of inherited breast cancers and more than ...

Breast Triple Stain (CK5 + p63 + CK 8/18)

The combination of CK5 + P63 + CK8/18 (Breast Triple Stain) can be extremely useful in distinguishing ...

CA15-3

CA15-3 has been detected in a wide spectrum of carcinomas such as breast carcinomas including ...

CA19-9

In normal tissues, the CA19-9 antigen has been demonstrated in ductal epithelium of the breast, ...

CA-125

CA-125 reacts with approximately 80% of epithelial ovarian neoplasms of serous, endometrioid, ...

Calcitonin

Calcitonin is secreted by thyroidal parafollicular cells of neuroectodermal origin, probably ...

Caldesmon

Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. ...

Calponin (CALP 1)

Calponin, a calmodulin, is involved in the regulation of smooth muscle contraction. The expression ...

Calretinin

Calretinin is the most specific and reproducible positive marker of epithelial mesothelioma. ...

Carbonic Anhydrase IX

Carbonic anhydrase IX (CAIX) is a cell surface transmembrane protein, which is predominantly ...

Carcinoembryonic Antigen (CEA) Monoclonal

CEA is usually demonstrated as a linear labeling of the apical poles of cells lining the glandular ...

Carcinoembryonic Antigen (CEA) Polyclonal

Polyclonal CEA stains a larger percentage of Cholangiocarcinomas compared with Hepatocellular ...

Caspase 3

Designed to provide information on cell death vs. cell proliferation rates.

Cathepsin D

Prognostic marker in many tumor types, especially breast cancer.

CD1a

At least five CD1 genes (CD1a, b, c, d, and e) have been identified. CD1a is expressed on cortical ...

CD2

CD2, the E-rosette receptor, is an extremely broad T-cell marker. This antibody immunolabels ...

CD3

The CD3 antigen is first detectable in early thymocytes and its appearance probably represents ...

CD4

CD4, a single chain transmembrane glycoprotein, is found on a T-cell subset (helper/inducer). ...

CD5

CD5, a transmembrane protein, is found on most thymocytes and immature peripheral T-cells. ...

CD7

CD7 is expressed on the majority of immature and mature T-lymphocytes and T-cell leukemia. ...

CD8

CD8 is a T-cell marker for the detection of cytotoxic/suppressor T-cells. CD8 is also detected ...

CD10

CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA), is expressed in early ...

CD11c

Useful in identification of cells of the macrophage/dendritic cell lineage in tissue.

CD15

CD15 (X-Hapten) plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. ...

CD19

Labels B-cells in normal and neoplastic tissue.

CD20

Positive staining (normal): Most B-cells (after CD19 and CD10 expression, before CD21/22 expression ...

CD21

CD21 (CR2, C3d receptor and EBV receptor) is expressed strongly on mature B-cells, follicular ...

CD22

CD22 expression is restricted to normal and neoplastic B-cells and is absent from other hemopoietic ...

CD23

CD23 is identical to low affinity IgE receptor found on B-cells. CD23 is expressed on a subpopulation ...

CD25

The interleukin-2 receptor is designated CD25. Originally isolated from T-lymphocytes, it ...

CD30

CD30 is a lymphocyte activation antigen, related to tumor necrosis factor. Positive staining ...

CD31

CD31 is a 130-kd transmembrane glycoprotein that is shared by vascular lining cells, megakaryocytes ...

CD33

Useful for identification of cells for myeloid and monocytic lineage, leukemias and myeloproliferative ...

CD34

CD34, a single chain transmembrane glycoprotein, is selectively expressed on human lymphoid ...

CD35

CD35 antigen is a transmembrane protein of 160-250 kD that binds complement components C3b ...

CD38

CD38 is a transmembrane protein, that is highly expressed on thymocytes. It is also present ...

CD42b

Expressed on megakaryocytes, platelets and their precursors.

CD43

CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is a cell surface glycoprotein ...

CD45

CD45 (Leukocyte Common Antigen, LCA) is comprised of at least four isoforms (CD45RA, CD45RB, ...

CD45RB

Expressed on mature B-lymphocytes and a majority of lymphomas and leukemias of B-cell origin.

CD45RO

CD45RO (an isoform of leukocyte common antigen) reacts with mature activated T-cells, most ...

CD56

CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed ...

CD57

CD57 is expressed on a subpopulation of 15-20% of peripheral blood mononuclear cells, about ...

CD61

CD61 (GPIIIa) is a glycoprotein found on megakaryocytes, platelets and their precursors. CD61 ...

CD68

CD68 is important for identifying macrophages in tissue sections. It stains macrophages in ...

CD74

Expression of the invariant chain of the HLA-DR antigen (CD74) by B-lymphocytes begins in ...

CD75

The CD75 protein has a molecular weight of approximately 53kD and is a marker of mature B- ...

CD79a

CD79a first appears at the pre B-cell stage and persists until the plasma cell stage where ...

CD99

CD99 (MIC2 gene product, E2) antigen is strongly expressed by Ewing’s sarcoma cells, primitive ...

CD123

Labels the plasmacytoid predendritic cells and may be helpful in diagnosing the Kikuchi-Fujimoto ...

CD138

CD138 (Syndecan-1) mediates cell adhesion, growth factors. Positive staining (normal): B-cell ...

CD163

CD163 antigen is restricted in its expression to the monocytic/macrophage lineage. It is present ...

CDX2

CDX2 is an intestine specific transcription factor that regulates both the proliferation and ...

CDX2/CK7 Double Stain

CDX2 is a homeobox gene that encodes an intestine-specific transcription factor. It is expressed ...

CEACAM5

CEACAM5 (CEA-related cell adhesion molecule 5, CEA) belongs to the carcinoembryonic antigen ...

Chromogranin A

Chromogranin is present in several elements of the diffuse neuroendocrine system (DNES), including ...

C-KIT

CD117 (c-kit) is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). ...

Collagen IV

Collagen IV is a major constituent of the basement membranes along with laminins and enactins. ...

CXCR4

CXCR4 is required to initiate proliferation and/or promote survival of breast cancer cells ...

Cyclin E

Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the cell cycle. ...

Cyclooxygenase-2

COX-2 is expressed in normal brain and kidney, activated macrophages, synoviocytes during inflammation ...

Cytokeratin - (CK - HMW/LMW) Double Stain

This cocktail can be useful in differentiation of the squamous cell carcinomas and adenocarcinomas. ...

Cytokeratin - High Molecular Weight

CK 903 (34betaE12) is a high molecular weight cytokeratin that reacts with all squamous epithelium ...

CYTOKERATIN 5

CK5 is a 58 kDa protein that is closely related to CK6. CK5 tissue distribution is in many ...

Cytokeratin 5/6

CK5/6 positivity is seen in nearly 100% of malignant mesotheliomas and in almost no lung adenocarcinomas. ...

Cytokeratin 7

This antibody reacts with proteins that are found in most ductal, glandular and transitional ...

Cytokeratin 8

Cytokeratin 8, 35betaH11 antibody, is reactive with the majority of epithelium and epithelial ...

Cytokeratin 14

CK14 belongs to the type A (acidic) subfamily of high molecular weight keratins and exists ...

Cytokeratin 17

CK17 is an excellent marker to distinguish myoepithelial cells from luminal epithelium of various ...

Cytokeratin 18

Stains most epithelial-derived tumors.

Cytokeratin 19

Cytokeratin 19 is a member of type I acidic subfamily of keratins. It is expressed in various ...

Cytokeratin 20

CK20 positivity is seen in the majority of adenocarcinomas of the colon, mucinous ovarian carcinomas, ...

Cytokeratin AE1/AE3 (Pan)

Monoclonal antibodies AE1 and AE3 recognize the acidic and basic subfamilies of cytokeratin ...

Cytokeratin CAM 5.2

Anti-Cytokeratin (CAM 5.2) has a primary reactivity with human keratin proteins that correspond ...

Cytokeratin OSCAR

CK OSCAR demonstrates a broad spectrum of cytokeratin reactivity. In normal tissues, OSCAR ...

Cytomegalovirus

Cytomegalovirus (CMV) is an opportunistic pathogen infecting lung, kidney, gut and other organs ...

D2-40

D2-40 identifies a 40 kDa O-linked sialoglycoprotein expressed by a variety of tissues, including ...

DBA.44

This antibody reacts with a subset of B-cells in the mantle zone and some immunoblasts outside ...

DCC

Gene is deleted in more than 70% of colorectal cancers. Lack of DCC protein expression is associated ...

Desmin

Desmin is an intermediate filament protein of both smooth and striated muscles. Antibody to ...

DOG-1

Dog1 is a cell surface protein of unknown function selectively expressed in GIST. Among GIST ...

DPC4

Loss of expression specific for pancreatic malignany (in-situ or invasive) vs. benign process. ...

EBV LMP-1 (EBV)

This antibody reacts strongly with EBV-positive lymphoblastoid cell lines and EBV infected ...

E-Cadherin

E-Cadherin is an adhesion protein that is expressed in cells of epithelial lineage. It stains ...

eIF4E

Overexpression induces cellular transformation, tumor growth and metastasis. Expression indicates ...

Epidermal Growth Factor Receptor (EGFR)

EGFR over-expression can occur in a variety of tumor types, including breast, prostate, ovarian, ...

Epithelial Membrane Antigen (EMA)

EMA antibody is a useful marker for staining many carcinomas. It stains normal and neoplastic ...

ERCC1

The mammalian ERCC1 (Excision Repair Cross-ComplementingRodent Repair Deficiency, Complementation ...

Estrogen Receptor (ER-1D5)

The expression of estrogen receptor has been related to the prognosis and response of breast ...

Factor VIII

Factor VIII-related antigen is a component of Factor VIII complex. Factor VIII-related antigen ...

Factor XIIIa

Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of ...

Fascin

Human fascin is a highly conserved actin-bundling protein. It is expressed predominantly in ...

Fli-1

Labels Ewing's Kaposis sarcoma, hemangiomas angiosarcomas and Merkel cell carcinoma.

Follicle Stimulating Hormone (FSH)

FSH is a pituitary hormone involved in the maturation of ovarian follicles and estrogen secretion ...

FOXP3

FOXP3 (transcriptional factor) is a central regulator of T-cell activity.

Gastrin

Gastrin, a polypeptide hormone, occurs naturally in three forms: gastrin-14, gastrin-17 and ...

Geminin

Geminin appears to play important roles in the progression of the cell cycle and cell proliferation, ...

Glial Fibrillary Acidic Protein (GFAP)

GFAP is the major protein found in astrocytes and its expression is evidence of astroglial ...

Glucagon (GLU)

Glucagon is used for the identification of tumors and hyperplasias of pancreatic islets. Antibody ...

Glutathione S-Transferase (GST)

GSTp is a cytosolic enzyme that catalyzes the conjugation of toxic compounds to glutathione ...

Glycophorin A

Glycophorin A (sialoglycoprotein alpha) is one of two transmembrane proteins exposed on the ...

Glypican 3

A useful marker to differentiate between benign (negative) and malignant (positive) liver diseases ...

Granzyme B

Labels activated human cytotoxic T-lymphocytes (CTL) and natural killer (NK) cells.

Gross Cystic Fluid Protein 15 (GCDFP-15)

This antibody is specific to a 15 kDa monomer protein called Gross Cystic Disease Fluid Protein-15 ...

Growth Hormone (GH)

GH is produced by the somatotroph cells in the pituitary. This marker is a useful in classification ...

HBME-1

HBME-1 is an antimesothelial monoclonal antibody that recognizes an unknown antigen on microvilli ...

Helicobacter Pylori

This antibody reacts with H. pylori on the surface and in the cytoplasm of epithelial cells ...

Hemoglobin A

Antibodies to Hemoglobin A react with the alpha chain of adult hemoglobin A. Antibodies to ...

Hepatitis B Core Antigen (HBVc)

Hepatitis B virus causes type B hepatitis and it belongs to the hepatovirus family. Hepatitis ...

Hepatitis B Surface Antigen (HBVs)

Hepatitis B virus causes type B hepatitis and it belongs to the hepatovirus family. It is spherical ...

HepPar-1

Anti-Hepatocyte Specific Antigen recognizes both benign and malignant liver derived tumors ...

HER-2 (HercepTest®)

HER-2 is an oncogene that is over-expressed in some breast carcinomas. The expected over-expression ...

Herpes Simplex 1 Antigen (HSV I)

Antibody reacts with HSV type 1 specific antigens and with antigens common for HSV types 1 ...

Herpes Simplex 2 Antigen (HSV II)

This antibody reacts with HSV type 2 specific antigens and with antigens common for HSV types ...

HLA-DR

This antibody stains a variety of cells expressing the HLA-DR antigen including B-lymphocytes, ...

HMB-45

Clone HMB45 recognizes a melanoma-specific antigen by reacting with melanoma cells, nevus cells ...

HMFG2

The carcinoma-associated antigen MAM6 is a mucus glycoprotein of molecular weight > 400 kD. ...

Human Chorionic Gonadotropin (HCG)

hCG is secreted in large quantities by the placenta and normally is found in maternal circulation ...

Human Herpesvirus, Type 8 (HHV 8)

HHV 8 is the likely etiological agent of Kaposi’s sarcoma (KS). HHV 8 encodes a latent nuclear ...

Human Papilloma Virus (HPV)

Infection with specific types of HPV has been associated with an increased risk of developing ...

Human Placental Lactogen (HPL)

Placental lactogen is a polypeptide hormone synthesized in syncytiotro-phoblastic cells of ...

IGG4

Autoimmune pancreatitis typically produces an enlarged pancreas with narrowing of the pancreatic ...

Immunoglobulin A (IGA)

IgA antibody reacts with immunoglobulin Ig alpha chains. It is useful in identifying leukemias, ...

Immunoglobulin D (IGD)

IgD antibody reacts with immunoglobulin Ig delta chains. This antibody is useful when identifying ...

Immunoglobulin G (IGG)

IgG antibody reacts with immunoglobulin Ig gamma chains. This antibody is useful when identifying ...

Immunoglobulin M (IGM)

IgM antibody reacts with immunoglobulin Ig mu chains. This antibody is useful when identifying ...

Inhibin

Anti-Inhibin alpha is an antibody against a peptide hormone which has a demonstrated utility ...

Insulin

Insulin is composed of a and b chains connected through the C-peptide. The main storage site ...

Kappa Light Chain Immunoglobulin

Antibody to the kappa light chain of immunoglobulin is reportedly useful in the identification ...

Ki-67

Ki-67 is a nuclear protein that is expressed in proliferating cells. Ki-67 is preferentially ...

Lambda Light Chain Immunoglobulin

Antibody to the lambda light chain of immunoglobulin is reportedly useful in the identification ...

Luteinizing Hormone (LH)

LH is a tropic hormone that modulates the secretory activity of other endocrine glands. It ...

Lysozyme

Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated ...

Mammaglobin

Mammaglobin is a breast-associated glycoprotein. Mammaglobin mRNA expression is breast specific ...

Melan A

Melan-A (MART-1, Melanoma Antigen Recognized by T-cells 1), is a differentiation antigen that ...

Mesothelin

Mesothelin is a 40 kD cell surface glycoprotein selectively expressed by mesothelial cells, ...

MGMT

Overexpression is associated with BCNU resistance in malignant gliomas.

MITF

MITF (microphthalmia transcription factor) is a transcription factor that regulates the development ...

MLH1 (hMLH1)

Mismatch repair genes perform an essential cellular function by repairing DNA mismatches that ...

MOC 31

Monoclonal antibody MOC-31 recognizes a membrane glycoprotein of 40kD molecular mass present ...

MSH2 (hMSH2)

Mismatch repair genes perform an essential cellular function by repairing DNA mismatches that ...

MSH6

Mismatch repair (MMR) genes results in failure to repair errors in repetitive sequences that ...

MUC1

MUC1 is a high molecular weight glycoprotein that is found on the apical surface of many glandular ...

MUC2

MUC2 expression is detected in such human tissues as normal colon, breast, prostate, salivary ...

MUC5

A marker of the gastric epithelial cell phonotype.

MUC6

Useful in differentiation of gastric cancer.

Multi-Drug Resistant Marker (MDR)

MDR-1 is membrane protein of the multi-drug resistance gene. It is associated with an efflux ...

MUM1

MUM1 is specific for the MUM1/IRF4 protein that is overexpressed in late plasma-cell-directed ...

Myeloperoxidase (MPO)

Myeloperoxidase is an important enzyme used by granulocytes during phagocytic lysis of foreign ...

Myo D1

Nuclear expression of MyoD1 is restricted to skeletal muscle tissue and has been demonstrated ...

Myogenin

Restricted to cells of skeletal muscle origin.

Myoglobin

Myoglobin is found in skeletal and cardiac muscle but not in smooth muscle. Because myoglobin ...

Napsin A

Napsin A has a specific function in normal alveolar epithelium and is proposed to play a role ...

Neuroblastoma (NB)

Recognizes human neuroblastoma (does not bind to other small round-cell tumors of childhood). ...

Neurofi lament (NF)

Neurofilaments are the intermediate filaments of neurons and their processes. Neurofilaments ...

Neuron Specific Enolase (NSE)

In normal tissue, most neurons and their axonal and dendritic processes stain strongly positive ...

OCT 4

A marker of classical semionoma and embryonal carcinoma.

OCT2

OCT2 is present in all B-cells expressing Ig. The combination of BOB1 and OCT2 stains is helpful ...

p16

p16 (p16 -INK4a, p16-MTS1, inhibitor of CDK4) is the product of the CDKN2 gene. It inhibits ...

p21

p21 is a cyclin dependent protein kinase inhibitor and is a member of a family of proteins ...

p27

p27 (KIP1) belongs to the family of cell cycle regulators that cause cell cycle arrest in the ...

p53

The product of the p53 gene is a nuclear phosphoprotein that regulates cell proliferation. ...

p57

P57 (Kip 2, CDKN 1C) is an inhibitor of several G1 cyclin complexes and is a negative regulator ...

p63

p63 is a homologue of the p53 gene and is necessary for normal breast and prostate development. ...

p120

Useful in the diagnostic distinction between lobular (cytoplasmic staining pattern) and ductal ...

P501S

P501S protein, also called the prostein, is a type IIIa plasma membrane protein which has been ...

p504S

Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic ...

Pancreatic Polypeptide (PP)

Pancreatic polypeptide is secreted by PP-cells of islet cell. It is also found in pancreatic ...

Pan-Melanoma (S100 + Melan A + Tyrosinase)

Mart-1(Melan A) and Tyrosinase are a cocktail staining DAB (brown) Cytoplasmic. S100 is the ...

Parathyroid Hormone (PTH)

Parathyroid hormone is expressed in normal parathyroid, parathyroid adenomas and primary and ...

Parvovirus

This monoclonal antibody clone, R92F6, recognizes acapsid protein of human parvovirus B19. ...

PAX2

Useful in the diagnosis of renal cell carcinoma.

PAX5

PAX-5 is a B-cell specific activator protein (BSAP). In early stages of B-cell development, ...

PAX-8

This gene is a member of the paired box (PAX) family of transcription factors. This family ...

PD1

Expressed on most T-cells and a small subset of B-cells in the light zone of germinal centers ...

PDGFRA

Activated receptors control cell growth, migration and differentiation and may be a useful ...

PDGFRB

Activated receptors control cell growth, migration and differentiation. May be a useful prognostic ...

Perforin

Perforin is a protein found in cytoplasmic granules of cytotoxic T-lymphocytes (CTLs). CTLs ...

PHH3

Detects mitotic cells.

Phosphorylated AKT

Akt is a signal transduction protein that plays a central role in inhibiting apoptosis in a ...

Placental Alkaline Phosphatase (PLAP)

Normally human PLAP is produced by syncytiotrophoblasts after the twelfth week of pregnancy. ...

PMS2

Mismatch repair (MMR) genes result in failure to repair errors in repetitive sequences that ...

Pneumocystis Carinii (P. carinii)

This antibody is specific to P. carinii. It stains P. carinii distinctly. The staining pattern ...

Prealbumin (TTR)

Prealbumin (TTR) is a hormone-binding protein that participates in the plasma transport of ...

Progesterone Receptor (PR636)

The expression of estrogen and progesterone receptors has been related to the prognosis and ...

Prolactin

Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water ...

Prostate Acid Phosphatase (PSAP)

Prostate specific acid phosphatase (PSAP) is a 100 kD glycoprotein present in high concentration ...

Prostate Specific Antigen (PSA)

Prostate specific antigen (PSA) is a glycoprotein with a molecular weight of 33-34 kD. It is ...

Prostate Specific Membrane Antigen

Prostate specific membrane antigen (PSMA) is a 750 amino acid type II membrane glycoprotein ...

Prostate Triple Stain (p63+CK HMW+p504S)

The combination of p63 + CK HMW + P504S (PIN-4 cocktail) can be extremely useful for diagnosing ...

PTEN

Controls cell proliferation, apoptosis and cell migration. A tumor suppressor gene implicated ...

PU.1

PU.1 is a transcription factor that has been shown to be important for normal B-cell development. ...

Pulmotype® lung cancer test

This test is an aid to the pathologist to further subclassify non-small cell lung cancer. CEACAM5 ...

RCC1

In normal kidney, RCC (gp200) is localized along the brush border of the proximal tubule. Of ...

Retinoblastoma Protein

RB is a tumor suppressor gene which functions as a negative regulator of the cell cycle by ...

S100

S100 belongs to the family of calcium binding proteins. Antibody to S100 stains Schwannomas, ...

Serotonin

Useful for characterization of carcinoids.

Simian Virus 40 (SV40)

Simian Virus 40 (SV40) is a polyomavirus that is found in both monkeys and humans. Like other ...

Smooth Muscle Myosin, Heavy Chain (SMMHC)

SMMS-1 is an antibody to smooth muscle myosin, heavy chain that reacts with human visceral ...

Somatostatin

Somatostatin is a useful marker of D-cells of pancreatic islet cells. D-cells are used to identify ...

Spirochete

Useful in identification of Spirochete (Treponema Pallidum).

Surfactant

Pulmonary surfactant apoproteins play essential roles in keeping alveoli from collapsing at ...

Survivin

Overexpressed in tumors; however, the level is low in most normal adult tissue.

Synaptophysin

Antibody to synaptophysin reacts with neuroendocrine neoplasms of neural as well as epithelial ...

Tartrate-Resistant Acid Phosphatase (TRAP)

TRAP ( isoenzyme) has been detected in human alveolar macrophages, osteoclasts, spleen and ...

Tau

Down-regulation of Tau expression in breast cancer cells increases sensitivity to apclitaxel.

T-CELL ANTIGEN RECEPTOR ßF1

TCRß is used as a phenotypic marker for TCR ß expressing T-cells. T-cell receptor (TCR) is ...

Terminal Deoxynucleotidyl Transferase (TDT)

TdT is considered to be a highly specific marker for the diagnosis and classification of acute ...

Thrombomodulin (TM)

Thrombomodulin is a plasma membrane-related glycoprotein that has anticoagulant activity. ...

Thymidylate Synthase (TS)

Antibody MAB4130 recognizes a 36 kDa protein identified as Thymidylate Synthase [TS], that ...

Thyroglobulin (TGB)

This antibody labels thyroglobulin in follicular epithelial cells of the thyroid and colloid. ...

Thyroid Stimulating Hormone (TSH)

TSH is a pituitary hormone of 28kDa that stimulates thyroid growth and production of thyroid ...

Thyroid Transcription Factor 1 (TTF-1)

TTF-1 is found only in thyroid and thyroid tumors regardless of histologic type, as well as ...

TIA - 1

TIA-1 (T-cell intracytoplasmic antigen) monoclonal antibody reacts with a 15 kDa cytoplasmic ...

Topoisomerase II Alpha

Topoisomerase II alpha is an essential nuclear enzyme involved in DNA replication and is a ...

Toxoplasma (Toxo)

Toxoplasma is a crescent shaped sporozoan that lives as an intracellular parasite in various ...

TRANSFORMING GROTH FACTOR- ALPHA

TGF-alpha is a polypeptide growth factor that binds to the epidermal growth factor receptor ...

Tryptase

This antibody labels a mast cell tryptase. It will also show reactivity to basophils, but to ...

Tuberculosis

Mycobacterium tuberculosis is the most common cause of tuberculosis. Immunohistochemical demonstration ...

Tyrosinase

Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin ...

Uroplakin III

Uroplakins (UPs) are a family of transmembrane proteins (UPs Ia, Ib, II and III) that are specific ...

VEGF

VEGF (vascular endothelial growth factor) is a glycoprotein involved in angiogenesis that promotes ...

Villin

This antibody recognizes villin, a cytoskeletal filament protein of 58 kD found in human renal ...

Vimentin (VIM)

Vimentin is the major intermediate filament in a variety of mesenchymal cells including endothelial ...

WT- 1

Wilm’s tumor susceptibility gene 1 protein (WT1) has diagnostic utility in the distinction ...

ZAP-70

B-cell chronic lymphocytic leukemia (B-CLL) is a disease with a highly variable clinical course; ...